D-48 | The Prevalence and Impact of Body Mass Index on the Outcomes of Patients Undergoing Transcatheter Mitral Valve Repair Using MitraClip: A National Inpatient Sample Analysis 2016 to 2020

Low body mass index (BMI) is associated with poor outcomes in patients who undergo various cardiac interventions. Studies on elevated BMI have produced mixed results. Our study aims to evaluate the impact of obesity in-hospital undergoing transcatheter mitral valve repair using MitraClip US. National Inpatient Sample (NIS) database (2016-2020) was analyzed identify underwent MitraClip. After excluding <18 years, protein-energy malnutrition and rapid weight loss, final population classified into Obese (BMI ≥ 30 Kg/m2) Non-obese (Normal/Overweight) 18.5 -29.9 cohorts. The primary outcome mortality, secondary periprocedural complication rates. 40,950 (MitraClip). 7.8% were identified as obese. more likely be female (50.6% vs. 43.9%, p<0.001) younger (mean age 70.7 76.5 compared non-obese patients. Using multivariate logistic regression model, no significant difference mortality odds ratio 0.90(CI, 0.45-1.82, p=0.771), cardiogenic shock 1.04 (0.68-1.62, p=0.834) myocardial infarction 0.7 (0.31-1.60, p0.402) when comparing obese respectively. had higher acute kidney injury 1.29 (1.02-1.65, p=0.034). suggests does not influence short-term